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Article

Role of the functional variant (-652T>G) in the XRCC4 promoter in prostate cancer.

Molecular biology reports - 1 Nov 2014

Shao Ning, Li JiuMing, Xu Bin, Wang Yang, Lu XiaoJie, Feng NingHan

Abstract excerpt

Several genes encoding DNA repair molecules have been proposed as cancer-susceptibility genes. Many studies have suggested that SNPs in XRCC4 could be implicated in altering the risk of prostate cancer (PCa). We examined the role of the functional variant (-652T>G) in the XRCC4 promoter in PCa. The transcriptional activity of XRCC4 gene was measured by luciferase assay. We performed real-time...

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Source

Identifiers

PMID: 25096509
DOI: 10.1007/s11033-014-3636-1

Genes

XRCC4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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