Article
An updated meta-analysis of XRCC4 polymorphisms and cancer risk based on 31 case-control studies.
Cancer biomarkers : section A of Disease markers - 1 Jan 2012
Shao Ning, Jiang Wen Yu, Qiao Di, Zhang Shi Ge, Wu Ye, Zhang Xiang Xiang, Hua Li Xin, Ding Yi, Feng Ning Han
Abstract excerpt
OBJECTIVE: Evidence is accumulating that several genes encoding DNA repair molecules may be cancer-susceptibility genes. Recently, SNPs in XRCC4, a member of DNA repair genes, have been implicated in altering the risk of various cancers. However, the results of these studies are inconclusive or controversial. To derive a more precise estimation, we performed an updated meta-analysis. METHODS: A comprehensive...
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