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Article

Role of the functional MKK4 promoter variant (-1304T>G) in a decreased risk of prostate cancer: case-control study and meta-analysis.

Journal of cancer research and clinical oncology - 1 Sept 2012

Shao Ning, Wang Yang, Lu Kai, Jiang Wen-Yu, Li Qi, Wang Ning, Feng Ning-Han, Hua Li-Xin

Abstract excerpt

PURPOSE: MKK4 has been suggested as a tumor suppressor. The functional variant (-1304T>G) in the MKK4 promoter has been implicated as a risk factor for many types of cancer. However, its role in prostate cancer (PCa) is unclear. To determine whether this SNP constitutes a risk factor for PCa susceptibility and to derive a more precise estimation of the associations between this SNP and cancer risk, we performed a...

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PMID: 22526163
DOI: 10.1007/s00432-012-1226-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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