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Article

The PXR rs7643645 polymorphism is associated with the risk of higher prostate-specific antigen levels in prostate cancer patients.

PloS one - 1 Jan 2014

Reyes-Hernández Octavio D, Vega Libia, Jiménez-Ríos Miguel A, Martínez-Cervera Pedro F, Lugo-García Juan A, Hernández-Cadena Leticia, Ostrosky-Wegman Patricia, Orozco Lorena, Elizondo Guillermo

Abstract excerpt

Levels of enzymes that determine testosterone catabolism such as CYP3A4 have been associated with prostate cancer (PCa) risk. Although some studies have related CYP3A4*1B allele, a gene polymorphism that modifies CYP3A4 expression level, with PCa risk, others have failed, suggesting that addition...

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Share to Cytochrome P-450 CYP3A
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24924803
DOI: 10.1371/journal.pone.0099974
PMCID: PMC4055777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24924803-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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