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Article

Polymorphisms of DNA repair genes are risk factors for prostate cancer.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2007

Hirata Hiroshi, Hinoda Yuji, Tanaka Yuichiro, Okayama Naoko, Suehiro Yutaka, Kawamoto Ken, Kikuno Nobuyuki, Majid Shahana, Vejdani Kaveh, Dahiya Rajvir

Abstract excerpt

DNA repair gene alterations have been shown to cause a reduction in DNA repair capacity. We hypothesised that DNA repair gene polymorphisms may be risk factors for prostate cancer (PC). To test this hypothesis, DNA samples from 165 cases of prostate cancer and healthy controls were analyzed by PCR-RFLP to determine the genotypic frequency of three DNA repair genes (XRCC1, XPC and XRCC7). We found that the...

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Source

Identifiers

PMID: 17196815
DOI: 10.1016/j.ejca.2006.11.005

Genes

XPC
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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