Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of metacaspase 1 in Plasmodium berghei development and apoptosis.

Molecular and biochemical parasitology - 1 May 2007

Le Chat Ludovic, Sinden Robert E, Dessens Johannes T

Abstract excerpt

The malaria parasite encodes a wide range of proteases necessary to facilitate its many developmental transitions in vertebrate and insect hosts. Amongst these is a predicted cysteine protease structurally related to caspases, named Plasmodium metacaspase 1 (PxMC1). We have generated Plasmodium berghei parasites in which the PbMC1coding sequence is removed and replaced with a green fluorescent reporter gene to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Caspases
Share to DNA, Protozoan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Protozoan

Share to Genes, Reporter

Share to Green Fluorescent Proteins

Share to Plasmodium berghei

Share to Protozoan Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17335919
DOI: 10.1016/j.molbiopara.2007.01.016
PMCID: PMC2075530

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of metacaspase 1 in Plasmodium berghei development and apoptosis.PMID 17335919Read ↗

Dissecting The role of Plasmodium metacaspase-2 in malaria gametogenesis and sporogonySemantic proximity Read ↗

Targeted disruption of Plasmodium falciparum cysteine protease, falcipain 1, reduces oocyst production, not erythrocytic stage growthSemantic proximity Read ↗

A novel genetic technique in Plasmodium berghei allows liver stage analysis of genes required for mosquito stage development and demonstrates that de novo heme synthesis is essential for liver stage development in the malaria parasiteSemantic proximity Read ↗

Plasmodium Protease ROM1 Is Important for Proper Formation of the Parasitophorous VacuoleSemantic proximity Read ↗

Targeting the Extrinsic Pathway of Hepatocyte Apoptosis Promotes Clearance of Plasmodium Liver InfectionSemantic proximity Read ↗

Inactivation of a Plasmodium apicoplast protein attenuates formation of liver merozoitesSemantic proximity Read ↗

The Roles of Two Clip Domain Serine Proteases in Innate Immune Responses of the Malaria Vector Anopheles gambiaeSemantic proximity Read ↗

Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production.Semantic proximity Read ↗

Apoptosis-like death as a feature of malaria infection in mosquitoesSemantic proximity Read ↗

Unique insertions within Plasmodium falciparum subtilisin-like protease-1 are crucial for enzyme maturation and activity.Semantic proximity Read ↗

A Plasmodium cysteine protease required for efficient transition from the liver infection stageSemantic proximity Read ↗

Bacteria- and IMD pathway-independent immune defenses against Plasmodium falciparum in Anopheles gambiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.