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Article

Single-nucleotide polymorphisms of DNA repair genes OGG1 and XRCC1: association with gallbladder cancer in North Indian population.

Annals of surgical oncology - 1 Jun 2009

Srivastava Anvesha, Srivastava Kshitij, Pandey Sachchida Nand, Choudhuri G, Mittal B

Abstract excerpt

BACKGROUND: DNA damage by endogenous or exogenous source of reactive oxygen species (ROS) plays an important role in induction and progression of various cancers. Physiologically, gallbladder is likely to be exposed to various ROS which leads to extensive DNA damage. Cells overcome the DNA damage by repair mechanisms. Genetic variants of OGG1 and XRCC1, important enzymes participating in base excision repair...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19266243
DOI: 10.1245/s10434-009-0354-3

Genes

XRCC1
OGG1

Provenance

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Single-nucleotide polymorphisms of DNA repair genes OGG1 and XRCC1: association with gallbladder cancer in North Indian population.PMID 19266243Read ↗

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