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Article

CRIM1, the Antagonist of BMPs, is a Potential Risk Factor of Cancer

24 Jul 2014

Abstract excerpt

Cysteine-rich motor neuron1 protein (CRIM1), a novel antagonist of bone morphogenetic proteins (BMPs), is reported to regulate the processing of BMPs preprotein into mature protein and the delivery of BMPs to the cell surface. Previous studies have shown that CRIM1 is an important player in regulating placental development, organogenesis, angiogenesis and kidney disease. Here, we propose that CRIM1 is a potential...

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PMID: 25088037
DOI: 10.2174/1568009614666140725094125

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