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Current status and prospects of GREM1 research in cancer (Review)

19 Jul 2023

Abstract excerpt

GREM1 is a secreted protein that antagonizes bone morphogenetic proteins (BMPs) and participates in critical biological processes, including embryonic development, organogenesis and tissue differentiation. Gremlin 1 (GREM1) is also an inhibitor of TGF-β and a ligand for vascular endothelial growth factor receptor 2. In addition, GREM1 can induce cells, participate in the process of epithelial-mesenchymal...

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PMID: 37614374
DOI: 10.3892/mco.2023.2665

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