Article
Calcium homeostasis is altered in skeletal muscle of spontaneously hypertensive rats: cytofluorimetric and gene expression analysis.
The American journal of pathology - 1 Oct 2014
Liantonio Antonella, Camerino Giulia M, Scaramuzzi Antonia, Cannone Maria, Pierno Sabata, De Bellis Michela, Conte Elena, Fraysse Bodvael, Tricarico Domenico, Conte Camerino Diana
Abstract excerpt
Hypertension is often associated with skeletal muscle pathological conditions related to function and metabolism. The mechanisms underlying the development of these pathological conditions remain undefined. Because calcium homeostasis is a biomarker of muscle function, we assessed whether it is altered in hypertensive muscles. We measured resting intracellular calcium and store-operated calcium entry (SOCE) in...
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