Article
Store-operated calcium entry: From physiology to tubular aggregate myopathy.
Current opinion in pharmacology - 1 Feb 2023
Protasi Feliciano, Girolami Barbara, Roccabianca Sara, Rossi Daniela
Abstract excerpt
Store-Operated Ca2+ entry (SOCE) is recognized as a key mechanism in muscle physiology necessary to refill intracellular Ca2+ stores during sustained muscle activity. For many years the cell structures expected to mediate SOCE in skeletal muscle fibres remained unknown. Recently, the identification of Ca2+ Entry Units (CEUs) in exercised muscle fibres opened new insights into the role of extracellular Ca2+ in...
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