Article
Calcium current in smooth muscle cells from normotensive and genetically hypertensive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 1994
Wilde D W, Furspan P B, Szocik J F
Abstract excerpt
Genetic hypertension results from numerous phenotypic expressions. We hypothesized that increased calcium current in vascular smooth muscle of genetically hypertensive animals is partly responsible for observed increases in agonist sensitivity, contractility, and calcium influx. Using adult, spon...
Topics
- 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
- Animals
- Calcium Channels
- Cell Separation
- Cerebrovascular Disorders
- Electric Conductivity
- Genetic Predisposition to Disease
- Hypertension
- Muscle, Smooth, Vascular
- Rats
- Rats, Inbred SHR
- Rats, Inbred WKY
- Time Factors