Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome

6 Feb 2020

Abstract excerpt

Inflammasomes are important for host defence against pathogens and homeostasis with commensal microbes. Here, we show non-haemolytic enterotoxin (NHE) from the neglected human foodborne pathogen Bacillus cereus is an activator of the NLRP3 inflammasome and pyroptosis. NHE is a non-redundant toxin to haemolysin BL (HBL) despite having a similar mechanism of action. Via a putative transmembrane region, subunit C of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammasome and immune disorders
Share to Pediatric health and respiratory diseases
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32029733
DOI: 10.1038/s41467-020-14534-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasomePMID 32029733Read ↗

The Bacillus cereus Hbl and Nhe tripartite enterotoxin components assemble sequentially on the surface of target cells and are not interchangeable.Semantic proximity Read ↗

The Food Poisoning Toxins of Bacillus cereusSemantic proximity Read ↗

Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPSSemantic proximity Read ↗

Production, Secretion and Biological Activity of Bacillus cereus EnterotoxinsSemantic proximity Read ↗

Bacterial Toxins Are a Never-Ending Source of Surprises: From Natural Born Killers to NegotiatorsSemantic proximity Read ↗

Hemolysin liberates bacterial outer membrane vesicles for cytosolic lipopolysaccharide sensingSemantic proximity Read ↗

Clostridial pore-forming toxins: powerful virulence factors.Semantic proximity Read ↗

Escherichia coli K88 activates NLRP3 inflammasome-mediated pyroptosis in vitro and in vivoSemantic proximity Read ↗

Clostridium perfringens virulence factors are nonredundant activators of the NLRP3 inflammasomeSemantic proximity Read ↗

Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not IntracellularSemantic proximity Read ↗

Non-Canonical Inflammasome Pathway: The Role of Cell Death and Inflammation in EhrlichiosisSemantic proximity Read ↗

The staphylococcal enterotoxin (SE) familySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.