Article
SecDF of Bacillus subtilis, a molecular Siamese twin required for the efficient secretion of proteins.
The Journal of biological chemistry - 14 Aug 1998
Bolhuis A, Broekhuizen C P, Sorokin A, van Roosmalen M L, Venema G, Bron S, Quax W J, van Dijl J M
Abstract excerpt
In the present studies, we show that the SecD and SecF equivalents of the Gram-positive bacterium Bacillus subtilis are jointly present in one polypeptide, denoted SecDF, that is required to maintain a high capacity for protein secretion. Unlike the SecD subunit of the pre-protein translocase of Escherichia coli, SecDF of B. subtilis was not required for the release of a mature secretory protein from the...
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