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Article

Global adaptive rank truncated product method for gene-set analysis in association studies.

Biometrical journal. Biometrische Zeitschrift - 1 Sept 2014

Vilor-Tejedor Natalia, Calle M Luz

Abstract excerpt

Gene set analysis (GSA) aims to assess the overall association of a set of genetic variants with a phenotype and has the potential to detect subtle effects of variants in a gene or a pathway that might be missed when assessed individually. We present a new implementation of the Adaptive Rank Truncated Product method (ARTP) for analyzing the association of a set of Single Nucleotide Polymorphisms (SNPs) in a gene...

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PMID: 25082012
DOI: 10.1002/bimj.201300192

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