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Article

MTHFR C677T polymorphism associated with breast cancer susceptibility: a meta-analysis involving 15,260 cases and 20,411 controls.

Breast cancer research and treatment - 1 Sept 2010

Zhang Jian, Qiu Li-Xin, Wang Zhong-Hua, Wu Xiang-Hua, Liu Xiao-Jian, Wang Bi-Yun, Hu Xi-Chun

Abstract excerpt

Published data on the association between MTHFR C677T polymorphism and breast cancer risk are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. Medline, PubMed, Embase, and Web of Science were searched. Crude ORs with 95% CIs were used to assess the strength of association between the MTHFR C677T polymorphism and breast cancer risk. The pooled ORs were performed...

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Source

Identifiers

PMID: 20143151
DOI: 10.1007/s10549-010-0783-5

Genes

MTHFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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