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Article

Docetaxel induces moderate ovarian toxicity in mice, primarily affecting granulosa cells of early growing follicles

1 Jul 2014

Abstract excerpt

Advances in cancer therapy have focused attention on the quality of life of cancer survivors. Since infertility is a major concern following chemotherapy, it is important to characterize the drug-specific damage to the reproductive system to help find appropriate protective strategies. This study investigates the damage on neonatal mouse ovary maintained in vitro for 6 days, and exposed for 24 h (on Day 2) to...

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Share to Ovarian cancer diagnosis and treatment
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PMID: 25080441
DOI: 10.1093/molehr/gau057

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