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Article

Impact of first-line cancer treatment on the follicle quality in cryopreserved ovarian samples from girls and young women

20 Jun 2019

Abstract excerpt

STUDY QUESTION: Does first-line chemotherapy affect the quality of ovarian pre-antral follicles and stromal tissue in a population of young patients? SUMMARY ANSWER: Exposure to first-line chemotherapy significantly impacts follicle viability, size of residual intact follicles, steroid secretion in culture and quality of the stromal compartment. WHAT IS KNOWN ALREADY: First-line chemotherapy is considered to have...

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Share to Ovarian cancer diagnosis and treatment
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PMID: 31411325
DOI: 10.1093/humrep/dez125

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