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Article

Chemotherapy-induced late transgenerational effects in mice.

PloS one - 17 Mar 2011

Kujjo Loro L, Chang Eun A, Pereira Ricardo J G, Dhar Shilpa, Marrero-Rosado Brenda, Sengupta Satyaki, Wang Hongbing, Cibelli Jose B, Perez Gloria I

Abstract excerpt

To our knowledge, there is no report on long-term reproductive and developmental side effects in the offspring of mothers treated with a widely used chemotherapeutic drug such as doxorubicin (DXR), and neither is there information on transmission of any detrimental effects to several filial generations. Therefore, the purpose of the present paper was to examine the long-term effects of a single intraperitoneal...

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Identifiers

PMID: 21437292
DOI: 10.1371/journal.pone.0017877
PMCID: PMC3060098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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