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Article

Hypoxia adaptations in the grey wolf (Canis lupus chanco) from Qinghai-Tibet Plateau.

PLoS genetics - 1 Jul 2014

Zhang Wenping, Fan Zhenxin, Han Eunjung, Hou Rong, Zhang Liang, Galaverni Marco, Huang Jie, Liu Hong, Silva Pedro, Li Peng, Pollinger John P, Du Lianming, Zhang XiuyYue, Yue Bisong, Wayne Robert K, Zhang Zhihe

Abstract excerpt

The Tibetan grey wolf (Canis lupus chanco) occupies habitats on the Qinghai-Tibet Plateau, a high altitude (>3000 m) environment where low oxygen tension exerts unique selection pressure on individuals to adapt to hypoxic conditions. To identify genes involved in hypoxia adaptation, we generated complete genome sequences of nine Chinese wolves from high and low altitude populations at an average coverage of 25×...

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Share to Acclimatization
Share to Adaptation, Physiological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Oxygen Consumption

Share to Selection, Genetic

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Source

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Identifiers

PMID: 25078401
DOI: 10.1371/journal.pgen.1004466
PMCID: PMC4117439

Genes

ANGPT1
EPAS1
RYR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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