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Article

Evidences for mutations in the histone modifying gene SETD2 as critical drivers in leukemia development.

Science China. Life sciences - 1 Sept 2014

Wang QianFei, Cheng Tao

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Topics

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Share to SETD2 gene
Share to Histone-Lysine N-Methyltransferase
Share to Histones
Share to Leukemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25077743
DOI: 10.1007/s11427-014-4702-6

Genes

SETD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

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Evidences for mutations in the histone modifying gene SETD2 as critical drivers in leukemia development.PMID 25077743Read ↗

Roles of SETD2 in Leukemia—Transcription, DNA-Damage, and BeyondSemantic proximity Read ↗

SETting the Stage for Cancer Development: SETD2 and the Consequences of Lost Methylation.Semantic proximity Read ↗

Identification of functional cooperative mutations of SETD2 in human acute leukemia.Semantic proximity Read ↗

Mutations of epigenetic regulators and of the spliceosome machinery in therapy-related myeloid neoplasms and in acute leukemias evolved from chronic myeloproliferative diseasesSemantic proximity Read ↗

SETD2: an epigenetic modifier with tumor suppressor functionality.Semantic proximity Read ↗

Histone variants: nuclear function and disease.Semantic proximity Read ↗

Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia.Semantic proximity Read ↗

Chromatin modification and disease.Semantic proximity Read ↗

Mechanisms of epigenetic regulation of leukemia onset and progression.Semantic proximity Read ↗

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia.Semantic proximity Read ↗

Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease.Semantic proximity Read ↗

SETD2 as a regulator of N6-methyladenosine RNA methylation and modifiers in cancer.Semantic proximity Read ↗

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