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Article

Genetic polymorphisms of CXCR5 and CXCL13 are associated with non-responsiveness to the hepatitis B vaccine.

Vaccine - 15 Sept 2014

Duan Zhaojun, Chen Xiangmei, Liang Zhenglun, Zeng Ying, Zhu Fengcai, Long Lu, McCrae Malcolm A, Zhuang Hui, Shen Tao, Lu Fengmin

Abstract excerpt

A cohort based study has been undertaken to investigate the possible association of genetic polymorphisms in genes functionally related to follicular T helper (TfH) cells with non-responsiveness to hepatitis B virus (HBV) vaccination. A total of 24 single nucleotide polymorphisms (SNPs) in 6 TfH related genes (CXCR5, ICOS, CXCL13, IL-21, BCL6 and CD40L) were investigated in 20 non-responders and 45 responders to...

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Source

Identifiers

PMID: 25077417
DOI: 10.1016/j.vaccine.2014.07.064

Genes

CXCR5
CXCL13
BCL6
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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