Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Rapid detection of mutations related to Mycobacterium leprae drug resistance by using Hp-rPCR (hairpin primer- real time PCR) method].

Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association - 1 Mar 2014

Kai Masanori

Abstract excerpt

Rapid and simple detection method of drug resistance bacteria is required. In the present study, Hp-rPCR (hairpin primer-real time PCR) was applied to Mycobacterium leprae genes to detect mutations. Target sites of the method were as follows: first base and second base on 53rd codon and second base on 55th codon infolP1 gene for dapsone resistance, first base on 441st codon and 451st codon and second base on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon
Share to Dapsone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Double-Blind Method

Share to Drug Resistance, Bacterial

Share to Mycobacterium leprae

Share to Quinolones

Share to Real-Time Polymerase Chain Reaction

Share to Rifampin

Source

Identifiers

PMID: 25076760
DOI: 10.5025/hansen.83.6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Rapid detection of mutations related to Mycobacterium leprae drug resistance by using Hp-rPCR (hairpin primer- real time PCR) method].PMID 25076760Read ↗

Rapid and Ultrasensitive Approach for the Simultaneous Detection of Multilocus Mutations to Distinguish Rifampicin-Resistant Mycobacterium tuberculosis.Semantic proximity Read ↗

[A new multiplex allele-specific polymerase chain reaction assay for detection of rifampin-resistant Mycobacterium tuberculosis].Semantic proximity Read ↗

[Sequence analysis on drug-resistant gene of rpoB in Mycobacterium tuberculosis L-forms among pneumoconiosis patients complicated with tuberculosis].Semantic proximity Read ↗

Detection of gene mutations related with drug resistance in<i>Mycobacterium leprae</i>from leprosy patients using Touch-Down (TD) PCRSemantic proximity Read ↗

[Drug resistance of multibacillary leprosy patients in Japan--results of molecular genetic analyses].Semantic proximity Read ↗

[Clinical application and evaluation of the detection of five drugs resistance genes in Mycobacterium tuberculosis].Semantic proximity Read ↗

[Molecular mechanism of the acquisition of new-quinolone resistance in Mycobacterium leprae and M. tuberculosis and rapid differentiation methods for resistant bacilli].Semantic proximity Read ↗

[Study on the molecular mechanism of multi-drug resistance in clinical isolates of Mycobacterium tuberculosis].Semantic proximity Read ↗

[Molecular mutations of rpoB gene of multidrug resistant Mycobacterium tuberculosis isolates from China].Semantic proximity Read ↗

[Detection of rpoB gene mutations in Mycobacterium tuberculosis].Semantic proximity Read ↗

[Application of M-RAPD technique to obtain the genomic fingerprints of various pathogenic microbials].Semantic proximity Read ↗

Mutations in genes related to drug resistance in Mycobacterium leprae isolates from leprosy patients in Korea.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.