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Article

Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study.

Diabetes - 1 May 2015

Törn Carina, Hadley David, Lee Hye-Seung, Hagopian William, Lernmark Åke, Simell Olli, Rewers Marian, Ziegler Anette, Schatz Desmond, Akolkar Beena, Onengut-Gumuscu Suna, Chen Wei-Min, Toppari Jorma, Mykkänen Juha, Ilonen Jorma, Rich Stephen S, She Jin-Xiong, Steck Andrea K, Krischer Jeffrey

Abstract excerpt

The Environmental Determinants of Diabetes in the Young (TEDDY) study prospectively follows 8,677 children enrolled from birth who carry HLA-susceptibility genotypes for development of islet autoantibodies (IA) and type 1 diabetes (T1D). During the median follow-up time of 57 months, 350 children developed at least one persistent IA (GAD antibody, IA-2A, or micro insulin autoantibodies) and 84 of them progressed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25422107
DOI: 10.2337/db14-1497
PMCID: PMC4407865

Genes

ERBB3
INS
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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