Article
The effect of the beta thalassemia mutation on the clinical severity of the sickle beta thalassemia syndrome.
Haematologica - 1 Jan 2000
Perseu L, Ristaldi M S, Dibenedetto S P, Testa R, Schilirò G, Pirastu M, Cao A
Abstract excerpt
In this study, we have defined the beta thalassemia mutation and characterized the beta globin haplotype and the alpha globin gene arrangement in a group of patients of Sicilian descent with beta (s)/beta thalassemia. We found that those patients carrying a beta(+) thalassemia mutation associated...
Topics
- Anemia, Sickle Cell
- Globins
- Hemoglobins
- Humans
- Mutation
- Thalassemia