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Article

A mild type of Hb S-beta(+)-thalassemia [-92(C-->T)] in a Sicilian family.

American journal of hematology - 1 Feb 1993

Divoky V, Baysal E, Schiliro G, Dibenedetto S P, Huisman T H

Abstract excerpt

Hematological data are presented for an adult Sicilian patient with a mild Hb S-beta(+)-thalassemia caused by a C-->T mutation at position -92 of the beta promoter. This mutation was identified by sequencing of amplified DNA and was confirmed by dot-blot analysis with specific probes. A comparison of levels of Hb S and Hb A in Hb S-beta-thalassemia patients with different beta-thalassemia alleles showed great...

Topics

Adult
Base Sequence
Child
DNA
Female
Gene Amplification
Hemoglobin A
Hemoglobin, Sickle
Humans
Male
Mutation
beta-Thalassemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8438884
DOI: 10.1002/ajh.2830420216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8438884-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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