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LeuO enhances butyrate‐induced virulence expression through a positive regulatory loop in enterohaemorrhagic E scherichia coli

29 Jul 2014

Abstract excerpt

Enterohaemorrhagic Escherichia coli (EHEC) causes bloody diarrhoea and other severe symptoms such as haemorrhagic uraemic syndrome. The expression of virulence genes on the locus for enterocyte effacement (LEE) and associated genes is regulated by a variety of factors, including transcriptional regulators and environmental signals. Butyrate, one of the major short-chain fatty acids present in the intestine,...

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PMID: 25069663
DOI: 10.1111/mmi.12737

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