Article
Global Regulation by Horizontally Transferred Regulators Establishes the Pathogenicity of Escherichia coli
25 Jan 2008
Abstract excerpt
Enterohemorrhagic Escherichia coli is an emerging pathogen that causes diarrhea and hemolytic uremic syndrome. Much of the genomic information that affects virulence is acquired by horizontal transfer. Genes necessary for attaching and effacing lesions are located in the locus for enterocyte effacement (LEE) pathogenicity island. LEE gene transcription is positively regulated by Ler, which is also encoded by the...
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