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Article

A novel role of CDX1 in embryonic epicardial development.

PloS one - 1 Jan 2014

Chu Min, Wang Libo, Wang Huan, Shen Ting, Yang Yanqin, Sun Yun, Tang Nannan, Ni Ting, Zhu Jun, Mailman Richard B, Wang Yuan

Abstract excerpt

The molecular mechanism that regulates epicardial development has yet to be understood. In this study, we explored the function of CDX1, a Caudal-related family member, in epicardial epithelial-to-mesenchymal transition (EMT) and in the migration and the differentiation of epicardium-derived progenitors into vascular smooth muscle cells. We detected a transient expression of CDX1 in murine embryonic hearts at...

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Share to Neurogenesis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic Stem Cells

Share to Endothelium, Vascular

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Share to Myocytes, Smooth Muscle

Source

Open in PubMed Open full text

Identifiers

PMID: 25068460
DOI: 10.1371/journal.pone.0103271
PMCID: PMC4113346

Genes

CDX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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