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Article

The role of azoles in the management of azole-resistant aspergillosis: from the bench to the bedside.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy - 1 Jul 2014

Seyedmousavi Seyedmojtaba, Mouton Johan W, Melchers Willem J G, Brüggemann Roger J M, Verweij Paul E

Abstract excerpt

Azole resistance is an emerging problem in Aspergillus fumigatus and is associated with a high probability of treatment failure. An azole resistance mechanism typically decreases the activity of multiple azole compounds, depending on the mutation. As alternative treatment options are limited and in some isolates the minimum inhibitory concentration (MIC) increases by only a few two-fold dilutions steps, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25066814
DOI: 10.1016/j.drup.2014.06.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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