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Article

Managing Azole Resistance in Aspergillus.

Medical mycology journal - 1 Jan 2026

Kushima Hisako, Ishii Hiroshi

Abstract excerpt

Azole antifungals are the cornerstone of therapy for aspergillosis, yet the global rise in azole-resistant Aspergillus fumigatus has become a major clinical concern. Resistance rates vary widely across regions, with particularly serious implications for chronic pulmonary aspergillosis (CPA), which requires long-term azole therapy. Resistance mechanisms largely involve cyp51A mutations, although additional genetic...

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Identifiers

PMID: 42219345
DOI: 10.3314/mmj.26.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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