Article
Molecular Tools for the Detection and Deduction of Azole Antifungal Drug Resistance Phenotypes in Aspergillus Species.
Clinical microbiology reviews - 1 Oct 2017
Dudakova Anna, Spiess Birgit, Tangwattanachuleeporn Marut, Sasse Christoph, Buchheidt Dieter, Weig Michael, Groß Uwe, Bader Oliver
Abstract excerpt
The incidence of azole resistance in Aspergillus species has increased over the past years, most importantly for Aspergillus fumigatus. This is partially attributable to the global spread of only a few resistance alleles through the environment. Secondary resistance is a significant clinical concern, as invasive aspergillosis with drug-susceptible strains is already difficult to treat, and exclusion of...
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