Article
Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis.
Arthritis and rheumatism - 1 Jan 2009
Hinks Anne, Barton Anne, Shephard Neil, Eyre Steve, Bowes John, Cargill Michele, Wang Eric, Ke Xiayi, Kennedy Giulia C, John Sally, Worthington Jane, Thomson Wendy
Abstract excerpt
OBJECTIVE: Juvenile idiopathic arthritis (JIA) is a chronic rheumatic disease of childhood. Two well-established genetic factors known to contribute to JIA susceptibility, HLA and PTPN22, account for less than half of the genetic susceptibility to disease; therefore, additional genetic factors have yet to be identified. The purpose of this study was to perform a systematic search of the genome to identify novel...
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