Article
Platelet recovery and survival measured in patients by quantitative polymerase chain reaction of mitochondrial DNA.
Transfusion - 1 Jan 2015
Doescher Andrea, Petershofen Eduard K, Hertenstein Bernd, Kraemer Doris, Casper Jochen, Schmidt Jörg-Peter, Müller Thomas H
Abstract excerpt
BACKGROUND: Mitochondrial (mt) DNA markers have been identified as potential targets for the quantification of endogenous and allogeneic platelets (PLTs) in the blood of individuals who received transfusions. Our goal was to develop a routine polymerase chain reaction (PCR) assay for ex vivo monitoring of PLT survival in patients after transfusion. STUDY DESIGN AND METHODS: Targets were selected for real-time...
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