Article
Genotyping patients with recent blood transfusions.
Epidemiology (Cambridge, Mass.) - 1 Nov 2003
Gong Michelle Ng, Sai Yang, Zhou Wei, Thompson B Taylor, Xu Li-Lian, Christiani David C
Abstract excerpt
BACKGROUND: Many studies have used polymerase chain reaction amplification (PCR) to genotype for common polymorphisms in intensive-care units (ICUs) where blood transfusions are common. Evidence that donor leukocytes in transfused blood can be detected by PCR of the recipient blood suggests that this minor population of donor white cells (microchimerism) can interfere with genotyping of allelic polymorphisms in...
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