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Article

Maternal homocysteine in pregnancy and offspring birthweight: epidemiological associations and Mendelian randomization analysis.

International journal of epidemiology - 1 Oct 2014

Yajnik Chittaranjan S, Chandak Giriraj R, Joglekar Charudatta, Katre Prachi, Bhat Dattatray S, Singh Suraj N, Janipalli Charles S, Refsum Helga, Krishnaveni Ghattu, Veena Sargoor, Osmond Clive, Fall Caroline H D

Abstract excerpt

BACKGROUND: Disturbed one-carbon (1-C) metabolism in the mother is associated with poor fetal growth but causality of this relationship has not been established. METHODS: We studied the association between maternal total homocysteine and offspring birthweight in the Pune Maternal Nutrition Study (PMNS, Pune, India) and Parthenon Cohort Study (Mysore, India). We tested for evidence of causality within a Mendelian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25052622
DOI: 10.1093/ije/dyu132
PMCID: PMC4190518

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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