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Article

Mendelian randomization analysis of the effect of maternal homocysteine during pregnancy, as represented by maternal MTHFR C677T genotype, on birth weight.

Journal of epidemiology - 5 Sept 2013

Lee Hye Ah, Park Eun Ae, Cho Su Jin, Kim Hae Soon, Kim Young Ju, Lee Hwayoung, Gwak Hye Sun, Kim Ki Nam, Chang Namsoo, Ha Eun Hee, Park Hyesook

Abstract excerpt

BACKGROUND: We used Mendelian randomization analysis to investigate the causal relationship between maternal homocysteine level, as represented by maternal methylenetetrahydrofolate reductase (MTHFR) C677T genotype, with the birth weight of offspring. METHODS: We recruited women at 24 to 28 weeks' gestation who visited Ewha Womans University Hospital for prenatal care during the period from August 2001 to...

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Identifiers

PMID: 23856949
DOI: 10.2188/jea.je20120219
PMCID: PMC3775531

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MTHFR

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