Article
Interplay between genetic and clinical variables affecting platelet reactivity and cardiac adverse events in patients undergoing percutaneous coronary intervention.
PloS one - 1 Jan 2014
Siller-Matula Jolanta M, Lang Irene M, Neunteufl Thomas, Kozinski Marek, Maurer Gerald, Linkowska Katarzyna, Grzybowski Tomasz, Kubica Jacek, Jilma Bernd
Abstract excerpt
Several clinical and genetic variables are associated with influencing high on treatment platelet reactivity (HTPR). The aim of the study was to propose a path model explaining a concurrent impact among variables influencing HTPR and ischemic events. In this prospective cohort study polymorphisms of CYP2C19*2, CYP2C19*17, ABCB1, PON1 alleles and platelet function assessed by Multiple Electrode Aggregometry were...
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