Article
Interaction and exposure modification: are we asking the right questions?
American journal of epidemiology - 1 Apr 2012
Weinberg Clarice R
Abstract excerpt
Most diseases arise not purely through genetic abnormalities nor purely through environmental causes, but as "complex" conditions brought about by the combined effects of genetic susceptibility factors, nongenetic experiences and exposures, and bad luck. Finding simple models capable of both characterizing such joint effects and providing new insight into pathogenesis remains an ongoing challenge in etiologic...
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