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Article

Epistasis between polymorphisms in ACVR2B and ADAMTS19 is associated with premature ovarian failure.

Menopause (New York, N.Y.) - 1 Feb 2015

Pyun Jung-A, Kim Sunshin, Kwack KyuBum

Abstract excerpt

OBJECTIVE: This study investigated whether epistasis between single nucleotide polymorphisms (SNPs) within ACVR2B (activin A receptor, type IIB) and ADAMTS19 (ADAM metallopeptidase with thrombospondin type 1 motif, 19) genes is associated with premature ovarian failure (POF). METHODS: One hundred twenty women with POF and 152 controls were recruited for stage I, and 1,641 additional female controls participated...

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Share to Activin Receptors, Type II
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25051287
DOI: 10.1097/GME.0000000000000285

Genes

ADAMTS19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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