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Article

Genome-wide association study in premature ovarian failure patients suggests ADAMTS19 as a possible candidate gene.

Human reproduction (Oxford, England) - 1 Sept 2009

Knauff Erik A H, Franke Lude, van Es Michael A, van den Berg Leonard H, van der Schouw Yvonne T, Laven Joop S E, Lambalk Cornelius B, Hoek Annemieke, Goverde Angelique J, Christin-Maitre Sophie, Hsueh Aaron J, Wijmenga Cisca, Fauser Bart C J M

Abstract excerpt

BACKGROUND: Spontaneous premature ovarian failure (POF) occurs in 1% of women and has major implications for their fertility and health. Besides X chromosomal aberrations and fragile X premutations, no common genetic risk factor has so far been discovered in POF. Using high-density single nucleotide polymorphism (SNP) arrays, we set out to identify new genetic variants involved in this condition. METHODS: A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19508998
DOI: 10.1093/humrep/dep197

Genes

ADAMTS19
BDNF
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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