Article
Multiple EphB receptors mediate dorsal-ventral retinotopic mapping via similar bi-functional responses to ephrin-B1.
Molecular and cellular neurosciences - 1 Nov 2014
McLaughlin Todd, Lim Yoo-Shick, Santiago Alicia, O'Leary Dennis D M
Abstract excerpt
The projection from the retina to the superior colliculus in mice is organized in a retinotopic map that develops through the formation and guidance of interstitial branches extended by retinal ganglion cell axons. Bidirectional branch guidance along the lateral-medial collicular axis is critical to mapping the dorsal-ventral retinal axis. EphB receptor tyrosine kinases expressed in an overall low to high...
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