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Article

Role of p53 in preadipocyte differentiation

7 Jul 2014

Abstract excerpt

Insulin resistance, diabetes and many kinds of cancers are common in overweight and obese individuals. The tumor suppressor p53 is important in securing genetic stability, but its role in the regulation of metabolic processes and cell differentiation remains unclear. We have investigated the role of p53 in adipocyte differentiation. Using 3T3-L1 cells, a mouse embryonic fibroblast preadipocyte model and DIO rat...

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PMID: 25045020
DOI: 10.1002/cbin.10334

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