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Toward understanding genomic instability, mitochondrial dysfunction and aging

21 Sept 2018

Abstract excerpt

The biology of aging is an area of intense research, and many questions remain about how and why cell and organismal functions decline over time. In mammalian cells, genomic instability and mitochondrial dysfunction are thought to be among the primary drivers of cellular aging. This review focuses on the interrelationship between genomic instability and mitochondrial dysfunction in mammalian cells and its...

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PMID: 30238623
DOI: 10.1111/febs.14663

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