Article
Analysis of novel mutations in BRCA1 in Iranian families with breast cancer.
Hereditas - 1 Jun 2014
Sadr-Nabavi Ariane, Dastpak Mahtab, Homaei-Shandiz Fatemeh, Bahrami Ahmad Reza, Bidkhori Hamid-Reza, Raeesolmohaddeseen Mahmood
Abstract excerpt
In Iran and the rest of the world, breast cancer (BC) is the most common malignancy in women. Familial history and age are significant risk factors for the development of this disease in Iran. Most hereditary BCs are associated with inherited mutations in the BRCA1 and BRCA2 genes. Some recent studies demonstrated that BRCA1 mutations are seen in high-risk women with family histories of BC. In this report we...
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