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Article

An interleukin-6 receptor polymorphism is associated with opisthorchiasis-linked cholangiocarcinoma risk in Thailand.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014

Prayong Pokpong, Mairiang Eimorn, Pairojkul Chawalit, Chamgramol Yaovalux, Mairiang Pisaln, Bhudisawasdi Vajarabhongsa, Sripa Banchob

Abstract excerpt

The cholangiocarcinoma (CCA) is a relatively rare cancer worldwide but it is highly prevalent in Thailand where the liver fluke, Opisthorchis viverrini is endemic. There are reports that interleukin 6 (IL-6) may play an important role in the pathogenesis of opisthorchiasis associated CCA. Functionally, IL-6 can act on target cells through its receptor, IL-6R, and IL-6R polymorphisms may affect the functional...

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PMID: 25041016
DOI: 10.7314/apjcp.2014.15.13.5443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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