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Article

Risk factors for cholangiocarcinoma in high-risk area of Thailand: role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms.

Cancer epidemiology - 1 Apr 2012

Songserm Nopparat, Promthet Supannee, Sithithaworn Paiboon, Pientong Chamsai, Ekalaksananan Tipaya, Chopjitt Peechanika, Parkin Donald Maxwell

Abstract excerpt

BACKGROUND AND AIM: Cholangiocarcinoma (CCA) is the most common cancer in Northeast Thailand. Endemicity of Opisthorchis viverrini (OV) - a known carcinogen - is responsible, but although infection is very common, the lifetime risk of CCA is only 5%. Other co-factors must exist, including aspects of lifestyle or diet along with variations in genetic susceptibility to them. Change in methylenetetrahydrofolate...

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Identifiers

PMID: 22189445
DOI: 10.1016/j.canep.2011.11.007

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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