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Article

MTHFR polymorphisms and Opisthorchis viverrini infection: a relationship with increased susceptibility to cholangiocarcinoma in Thailand.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Songserm Nopparat, Promthet Supannee, Sithithaworn Paiboon, Pientong Chamsai, Ekalaksananan Tipaya, Chopjitt Peechanika, Parkin Donald Maxwell

Abstract excerpt

Opisthorchis viverrini (OV) infection is the major risk factor for cholangiocarcinoma (CCA). Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme in folate metabolism. Change in MTHFR activity may influence both DNA methylation and synthesis, crucial steps in carcinogenesis. This st...

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PMID: 21875294

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21875294-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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