Article
The role of the area postrema in the anorectic effects of amylin and salmon calcitonin: behavioral and neuronal phenotyping.
The European journal of neuroscience - 1 Oct 2014
Braegger Fiona E, Asarian Lori, Dahl Kirsten, Lutz Thomas A, Boyle Christina N
Abstract excerpt
Amylin reduces meal size by activating noradrenergic neurons in the area postrema (AP). Neurons in the AP also mediate the eating-inhibitory effects of salmon calcitonin (sCT), a potent amylin agonist, but the phenotypes of the neurons mediating its effect are unknown. Here we investigated whether sCT activates similar neuronal populations to amylin, and if its anorectic properties also depend on AP function....
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