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Article

Copy number variable microRNAs in schizophrenia and their neurodevelopmental gene targets.

Biological psychiatry - 15 Jan 2015

Warnica William, Merico Daniele, Costain Gregory, Alfred Simon E, Wei John, Marshall Christian R, Scherer Stephen W, Bassett Anne S

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are key regulators of gene expression in the human genome and may contribute to risk for neuropsychiatric disorders. miRNAs play an acknowledged role in the strongest of genetic risk factors for schizophrenia, 22q11.2 deletions. We hypothesized that in schizophrenia there would be an enrichment of other rare copy number variants (CNVs) that overlap miRNAs. METHODS: Using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25034949
DOI: 10.1016/j.biopsych.2014.05.011
PMCID: PMC4464826

Genes

CAPRIN1
NEDD4
NTRK2
PAK2
RHOA
SYNGAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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